Telegram is a popular IM platform that is famous for its openness. A lot of applications are being discovered with their public Bot API and User API. Exposed as an HTTP interface, the Bot API is more popular on Telegram, but to interact with a bot, we still need to expose its User API, which is using an original protocol named MTProto. Below is my simple code snipped that sends a message to a bot and mark its first reply as read, using Pyrogram — a Python wrapping of MTProto.